Acute toxicity evaluation of a thiazolo arene ruthenium (II) complex in rats
详细信息 查看全文
- 作者：Adriana Grozava ; adriana.ignat@umfcluj.ro" class="auth_mail" title="E-mail the corresponding author ; Viorel Miclausb ; vmiclaus@usamvcluj.ro" class="auth_mail" title="E-mail the corresponding author ; Oliviu Vostinaruc ; oliviu.vostinaru@umfcluj.ro" class="auth_mail" title="E-mail the corresponding author ; Steliana Ghibuc ; stelianaghibu@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Cristian Berced ; cristi.berce@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Ioana Rotare ; cristina.rotar@umfcluj.ro" class="auth_mail" title="E-mail the corresponding author ; Cristina Mogosanc ; cmogosan@umfcluj.ro" class="auth_mail" title="E-mail the corresponding author ; Bruno Therrienf ; bruno.therrien@unine.ch" class="auth_mail" title="E-mail the corresponding author ; Felicia Loghing ; floghin@umfcluj.ro" class="auth_mail" title="E-mail the corresponding author ; Daniela-Saveta Popag ; dpopa@umfcluj.ro" class="auth_mail" title="E-mail the corresponding author
- 关键词：Acute toxicity ; Thiazole ; Arene ruthenium complexes
- 刊名：Regulatory Toxicology and Pharmacology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：80
- 期：Complete
- 页码：233-240
- 全文大小：4737 K
文摘
- class="listitem" id="list_ulist0010">
- class="label">•
The acute toxicity of a thiazolo arene ruthenium (II) complex was evaluated in rats.
- class="label">•
The substance was very well tolerated orally.
- class="label">•
The hematological profile was not modified at any of the tested doses.
- class="label">•
Structural modifications were identified only in the spleen.