Alfalfa dwarf cytorhabdovirus P protein is a local and systemic RNA silencing supressor which inhibits programmed RISC activity and prevents transitive amplification of RNA silencing
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- 作者：Nicolá ; s Bejerman1 ; nicobejerman@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Krin S. Mann2 ; krinpreet.mann@canada.ca" class="auth_mail" title="E-mail the corresponding author ; Ralf G. Dietzgen r.dietzgen@uq.edu.au" class="auth_mail" title="E-mail the corresponding author
- 关键词：Alfalfa dwarf cytorhabdovirus ; Phosphoprotein ; RNA silencing suppression ; Protein-protein interactions ; Argonaute proteins ; Transitivity
- 刊名：Virus Research
- 出版年：2016
- 出版时间：15 September 2016
- 年：2016
- 卷：224
- 期：Complete
- 页码：19-28
- 全文大小：1967 K
文摘
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Alfalfa dwarf virus P protein has a weak local RSS activity.
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Alfalfa dwarf virus P strongly suppresses systemic RNA silencing.
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Alfalfa dwarf virus P interacts with AGO1 and AGO4.
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Alfalfa dwarf virus P inhibits miRNA-guided AGO1 cleavage.
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Alfalfa dwarf virus P prevents the production of secondary siRNAs.