How B-Type Natriuretic Peptide (BNP) and Body Weight Changes Vary in Heart Failure With Preserved Ejection Fraction Compared With Reduced Ejection Fraction: Secondary Results of the HABIT (HF Assessment With BNP in the Home) Trial
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- 作者：Alan S. Maisel ; MD1 ; 2 ; amaisel@ucsd.edu" class="auth_mail" title="E-mail the corresponding author ; Kevin S. Shah ; MD3 ; Denise Barnard ; MD1 ; Brian Jaski ; MD4 ; Geir Frivold ; MD5 ; John Marais ; MD6 ; Maged Azer ; MD7 ; Michael I. Miyamoto ; MD8 ; Dawn Lombardo ; DO ; MS2 ; Damon Kelsay ; MD9 ; Navaid Iqbal ; MD1 ; Pam R. Taub ; MD2 ; Ken Kupfer ; PhD10 ; Elizabeth Lee ; BS1 ; Paul Clopton ; MS1 ; Michael Zile ; MD11 ; Barry Greenberg ; MD2
- 关键词：Home monitoring ; heart failure ; natriuretic peptide ; preserved ejection fraction
- 刊名：Journal of Cardiac Failure
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：22
- 期：4
- 页码：283-293
- 全文大小：382 K
文摘
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HFpEF patients are more often female, older, more obese, and with lower BNP than patients with HFrEF.
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HFpEF patients have more frequent rises of BNP rises and less frequent incidences of weight gain.
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Patients with HFpEF demonstrates more day-to-day fluctuations in BNP than patients with HFrEF.
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Patients HFpEF and a rapid BNP rise >200 pg/mL in 3 days showed significant association with ADHF.
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Future studies investigating separate BNP and weight thresholds in outpatients with HFpEF and HFrEF should be investigated.