Multiplex assay reliability and long-term intra-individual variation of serologic inflammatory biomarkers

详细信息    查看全文

• 作者：Heather S. McKay^a ; ^{hmckay4@jhu.edu} ; Joseph B. Margolick^b ; Otoniel Martí ; nez-Maza^c ; ^d ; ^e ; ^f ; Joseph Lopez^b ; John Phair^g ; Giovanna Rappocciolo^h ; Thomas N. Dennyⁱ ; Larry I. Magpantay^c ; Lisa P. Jacobson^a ; Jay H. Bream^b
• 关键词：BAFF ; B-cell activating factor ; BMI ; body mass index ; CI ; confidence interval ; CCL11 ; C-C motif ligand 11 ; CV ; coefficient of variation ; CXCL8 ; C-X-C motif ligand 8 ; GM-CSF ; granulocytemacrophage colony-stimulating factor ; HCV ; hepatitis C virus ; HIV ; human immunodeficiency virus ; ICC ; intraclass correlation coefficient ; IFN ; interferon ; IL ; interleukin ; IQR ; interquartile range ; LLOD ; lower limit of detection ; sIL-2Rα ; soluble IL-2 receptor alpha ; MACS ; Multicenter AIDS Cohort Study ; sCD14 ; sol
• 刊名：Cytokine
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：90
• 期：Complete
• 页码：185-192
• 全文大小：815 K
• 卷排序：90

文摘

CCLL, CCL2, CCL13, and CCL4 exhibit strong within-person tracking up to 15 years apart. CXCL13 exhibits strong tracking only up to 8 years between measurements. CXCL10, CCL17, IL-10, IL-12p70, BAFF, sCD14, sCD27, sgp130, sIL-2Rα, and sTNF-R2 track moderately up to 15 years apart. IL-6 and TNF-α exhibit fair tracking up to 15 years between measurements. CXCL8 exhibits fair tracking only up to 4 years between measurements.