Outcomes of Allogeneic Stem Cell Transplantation in Elderly Patients with Acute Myeloid Leukemia: A Systematic Review and Meta-analysis
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- 作者：Armin Rashidi1 ; arashidi@dom.wustl.edu" class="auth_mail" title="E-mail the corresponding author ; Maryam Ebadi2 ; Graham A. Colditz3 ; John F. DiPersio1
- 关键词：Allogeneic ; Elderly ; Leukemia ; Outcome ; Reduced-intensity ; Transplantation
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：22
- 期：4
- 页码：651-657
- 全文大小：1182 K
文摘
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Elderly patients with acute myeloid leukemia are often undertreated.
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Transplantation outcomes in elderly patients with acute myeloid leukemia are poorly defined.
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A meta-analysis shows efficacy of allografting in elderly patients with acute myeloid leukemia and little publication bias.
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Thirty-five percent of elderly patients with acute myeloid leukemia are alive and in remission 3 years after transplantation.
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Age should not be the sole factor in making treatment decisions in elderly patients with acute myeloid leukemia.