Control of data quality for population-based cancer survival analysis

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• 作者：Ruoran Li ; ^{ruoran.li@lshtm.ac.uk" class="auth_mail} ; Louise Abela ; Jonathan Moore ; Laura M. Woods ; Ula Nur ; Bernard Rachet ; Claudia Allemani ; Michel P. Coleman
• 关键词：Cancer ; Survival ; Research design ; Population register ; Epidemiology
• 刊名：Cancer Epidemiology
• 出版年：June 2014
• 年：2014
• 卷：38
• 期：3
• 页码：314-320
• 全文大小：436 K

文摘

Population-based cancer survival is an important measure of the overall effectiveness of cancer care in a population. Population-based cancer registries collect data that enable the estimation of cancer survival. To ensure accurate, consistent and comparable survival estimates, strict control of data quality is required before the survival analyses are carried out. In this paper, we present a basis for data quality control for cancer survival.

Methods

We propose three distinct phases for the quality control. Firstly, each individual variable within a given record is examined to identify departures from the study protocol; secondly, each record is checked and excluded if it is ineligible or logically incoherent for analysis; lastly, the distributions of key characteristics in the whole dataset are examined for their plausibility.

Results

Data for patients diagnosed with bladder cancer in England between 1991 and 2010 are used as an example to aid the interpretation of the differences in data quality. The effect of different aspects of data quality on survival estimates is discussed.

Conclusions

We recommend that the results of data quality procedures should be reported together with the findings from survival analysis, to facilitate their interpretation.