TLR21's agonists in combination with Aeromonas antigens synergistically up-regulate functional TLR21 and cytokine gene expression in yellowtail leucocytes
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- 作者：Martha Reyes-Becerrila ; Felipe Ascencio-Vallea ; Ikuo Hironob ; Hidehiro Kondob ; Walissara Jirapongpairojb ; Maria Angeles Estebanc ; Erika Alamilloa ; Carlos Anguloa ; eangulo@cibnor.mx" class="auth_mail" title="E-mail the corresponding author
- 关键词：TLR21 ; Agonist TLRs ; Aeromonas antigens ; Cytokine gene expression ; Seriola lalandi
- 刊名：Developmental & Comparative Immunology
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：61
- 期：Complete
- 页码：107-115
- 全文大小：2659 K
文摘
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TLR21gene was identified and characterized in Seriola lalandi.
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TLR21 was up-regulated after TLR agonists plus Aeromonas antigens stimulation.
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Both IL-1β and TNF-α were strongly enhanced after TLR agonists and Aeromonas antigens stimulation.