Identification of rearranged sequences of HPV16 DNA in precancerous and cervical cancer cases
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- 作者：D. Tsakogiannisa ; M. Bletsaa ; Z. Kyriakopouloua ; T.G. Dimitrioua ; C. Kotsovassilisb ; E. Panotopoulouc ; P. Markoulatosa ; markoulatos@bio.uth.gr" class="auth_mail" title="E-mail the corresponding author
- 关键词：HPV16 ; Integration ; Rearrangements ; Caski ; Concatamers
- 刊名：Molecular and Cellular Probes
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：30
- 期：1
- 页码：6-12
- 全文大小：916 K
文摘
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The study focused on detection of rearranged sequences of HPV16 in clinical samples.
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Two distinct rearranged viral sequences were identified.
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Rearrangements encompass the junction of noncontiguous regions with inverted orientation.
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Detection of rearrangements may provide data about the presence of chromosomal damages.