Altered dynamics of brain connectivity in major depressive disorder at-rest and during task performance

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• 作者：Fabio Sambataro^a ; ^{fabio.sambataro@uniud.it} ; ^{sambatarof@gmail.com} ; Eleonora Visintin^b ; Nadja Doerig^c ; Janis Brakowski^d ; Martin Grosse Holtforth^e ; Erich Seifritz^d ; ^f ; ^g ; Simona Spinelli^f ; ^g ; ^h ; ^{spinellisimona@gmail.com}
• 关键词：Default mode network ; Executive network ; Major depressive disorder ; Functional magnetic resonance imaging ; Functional connectivity ; Low frequency oscillations
• 刊名：Psychiatry Research: Neuroimaging
• 出版年：2017
• 出版时间：30 January 2017
• 年：2017
• 卷：259
• 期：Complete
• 页码：1-9
• 全文大小：710 K
• 卷排序：259

文摘

Several intrinsic networks are functionally altered in major depressive disorder. Whether these functional alterations are present at rest and during task is unclear. The DMN and executive network show altered pattern of neural connectivity during rest and task. The salience network shows increased low frequency oscillations (LFO) amplitude during task only. The motor and dorsal attention networks show reduced LFO amplitude during rest and task.