Elemental distribution in human femoral head

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• 作者：C. Santos^a ; ^b ; ^c ; ^{catia.santos@itn.pt" class="auth_mail} ; M. Fonseca^a ; ^b ; ^e ; V. Corregidor^c ; H. Silva^a ; ^b ; ^c ; H. Luí ; s^a ; ^b ; A.P. Jesus^a ; ^b ; J. Branco^d ; L.C. Alves^b ; ^c
• 关键词：Osteoporosis ; Ion beam analysis ; PIXE ; EBS ; Trace elements
• 刊名：Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
• 出版年：15 July 2014
• 年：2014
• 卷：331
• 期：Complete
• 页码：266-270
• 全文大小：1121 K

文摘

Osteoporosis is the most common bone disease with severe symptoms and harmful effects on the patient quality of life. Because abnormal distribution and concentration of the major and trace elements may help to characterize the disease, ion beam analysis is applied to the study of bone samples. Proton Induced X-ray Emission and Elastic Backscattering Spectrometry are applied for qualitative and quantitative analysis of an osteoporotic bone sample, for the determination of the Ca/P ratio and analysis of the distribution of major and trace elements. The analysis was made both in trabecular and cortical bone and the results are in agreement with the information found in literature.