Cardiovascular disease in patients with osteogenesis imperfecta — a nationwide, register-based cohort study
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Osteogenesis imperfecta (OI) is a hereditary disease of connective tissue.

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Patients have increased risk of heart failure.

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Patients have increased risk of atrial fibrillation or flutter.

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Patients have increased risk of aortic and mitral valvulopathies.

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Adult patients with OI could benefit from regular ECG and echocardiography.

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