Genetic variability in E6, E7, and L1 genes of human papillomavirus genotype 52 from Southwest China
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- 作者：Yiwen Zhang1 ; zyw0417@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Man Cao1 ; 465220698@qq.com" class="auth_mail" title="E-mail the corresponding author ; Mengting Wang 442364812@qq.com" class="auth_mail" title="E-mail the corresponding author ; Xianping Ding ; brainding@scu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Yaling Jing 572175030@qq.com" class="auth_mail" title="E-mail the corresponding author ; Zuyi Chen 514373742@qq.com" class="auth_mail" title="E-mail the corresponding author ; Tengjiao Ma 553685346@qq.com" class="auth_mail" title="E-mail the corresponding author ; Honghan Chen 443742839@qq.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：HPV ; human papillomavirus ; ORF ; open reading frame ; BEB ; Bayes empirical Bayes
- 刊名：Gene
- 出版年：2016
- 出版时间：1 July 2016
- 年：2016
- 卷：585
- 期：1
- 页码：110-118
- 全文大小：630 K
文摘
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HPV-52 E6–E7 and L1 genes were sequenced to identify genetic variants.
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Amino-acid mutations related to secondary structure may affect protein function.
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Neighbor-joining trees were constructed for E6–E7 and L1 gene sequences.
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Selection pressures acting on E6–E7 and L1 genes were estimated.
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Positive selection was identified as a driver of genetic changes.