Polymorphisms in the long non-coding RNA CDKN2B-AS1 may contribute to higher systolic blood pressure levels in hypertensive patients
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- 作者：Burcu Bayoglua ; burcubayoglu@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; burcu.bayoglu@istanbul.edu.tr" class="auth_mail" title="E-mail the corresponding author ; Husniye Yukselb ; Huseyin Altug Cakmakc ; Ahmet Diricand ; Mujgan Cengiza
- 关键词：Hypertension ; Chromosome 9p21.3 ; CDKN2A/B ; CDKN2B-AS1 ; Genetic variation ; Haplotypes
- 刊名：Clinical Biochemistry
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：49
- 期：10-11
- 页码：821-827
- 全文大小：449 K
文摘
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HT is associated with the rs10757274, rs2383207, rs10757278, and rs1333049 SNPs.
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The rs1333049 GG genotype correlates with elevated systolic blood pressure levels.
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The rs2383207 AA genotype correlates with elevated resting glucose levels.
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The GG, GA, and AG haplotypes in block 1 correlate with HT.
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The GC and AG haplotypes in block 2 correlate with HT.