Identification of the Bcl-2 family protein gene BOK from orange-spotted grouper (Epinephelus coioides) involved in SGIV infection
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- 作者：Jia Caia ; b ; c ; 1 ; Dapeng Yua ; b ; c ; 1 ; Shina Weid ; Jufen Tanga ; b ; c ; Yishan Lua ; b ; c ; Zaohe Wub ; c ; Qiwei Qind ; qinqw@scsio.ac.cn" class="auth_mail" title="E-mail the corresponding author ; Jichang Jiana ; b ; c ; jianjc@gdou.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Epinephelus coioides ; BOK ; Singapore grouper iridovirus (SGIV) ; Viral gene ; Viral replication
- 刊名：Fish & Shellfish Immunology
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：52
- 期：Complete
- 页码：9-15
- 全文大小：1502 K
文摘
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Ec-BOK was cloned from orange-spotted grouper, Epinephelus coioides.
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Ec-BOK distributed in all examined tissues.
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Ec-BOK was up-regulated after SGIV infection in vitro.
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Over-expression of Ec-BOK decreased virus replication in vitro.