Frozen section evaluation of margins in radical prostatectomy specimens: a contemporary study and literature review
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- 作者：Amberly L. Nunez ; M.D.a ; 1 ; amberly.nunez@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Giovanna A. Giannico ; M.D.b ; giovanna.giannico@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author ; Faisal Mukhtar ; M.D.a ; 2 ; fmukhtar@ufl.edu" class="auth_mail" title="E-mail the corresponding author ; Virginia Dailey ; M.D.a ; 3 ; virginialeedailey@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Rizk El-Galley ; M.D.c ; 4 ; relgall50@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Omar Hameed ; M.D.b ; omar.hameed@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Frozen section ; Prostate cancer ; Positive surgical margin ; Radical prostatectomy ; Biochemical recurrence
- 刊名：Annals of Diagnostic Pathology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：24
- 期：Complete
- 页码：11-18
- 全文大小：4630 K
文摘
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We investigated the use of frozen sections (FSs) at radical prostatectomy (RP).
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Sensitivity and specificity were 85% and 100% for diagnosis of adenocarcinoma.
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Positive FS was associated with perineural invasion on biopsy and higher stage at RP.
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Accuracy of FS in predicting the overall prostatectomy final margin status was 81%.
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We suggest that FS has limited, if any predictive utility, for final margin status.