Risk and course of motor complications in a population-based incident Parkinson's disease cohort
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- 作者：Anders Bjornestada ; d ; anders.bjornestad@outlook.com" class="auth_mail" title="E-mail the corresponding author ; Elin B. Forsaaa ; d ; elin.bjelland.forsaa@sus.no" class="auth_mail" title="E-mail the corresponding author ; Kenn Freddy Pedersena ; d ; kenn.freddy.pedersen@sus.no" class="auth_mail" title="E-mail the corresponding author ; Ole-Bjorn Tysnesb ; c ; ole-bjorn.tysnes@helse-bergen.no" class="auth_mail" title="E-mail the corresponding author ; Jan Petter Larsena ; jpl@sus.no" class="auth_mail" title="E-mail the corresponding author ; Guido Alvesa ; d ; algu@sus.no" class="auth_mail" title="E-mail the corresponding author
- 关键词：Parkinson's disease ; Motor complications ; Motor fluctuations ; Dyskinesias ; Risk factors
- 刊名：Parkinsonism & Related Disorders
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：22
- 期：Complete
- 页码：48-53
- 全文大小：465 K
文摘
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Motor complications affected over 50% in the first 5 years of Parkinson's disease.
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Dopamine depletion is indicated as an important cause.
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Early levodopa treatment was not associated with motor complications.
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Motor complications were mild in the majority and reversible in more than 35%.
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No patients required advanced treatment during the first 5 years after diagnosis.