Efficacy of a trivalent influenza vaccine against seasonal strains and against 2009 pandemic H1N1: A randomized, placebo-controlled trial
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- 作者：William J.H. Mcbridea ; john.mcbride@jcu.edu.au" class="auth_mail" title="E-mail the corresponding author ; Walter P. Abhayaratnab ; c ; walter.abhayaratna@act.gov.au" class="auth_mail" title="E-mail the corresponding author ; Ian Barrd ; Ian.Barr@influenzacentre.org" class="auth_mail" title="E-mail the corresponding author ; Robert Booye ; Robert.booy@health.nsw.gov.au" class="auth_mail" title="E-mail the corresponding author ; Jonathan Carapetisf ; jonathan.carapetis@telethonkids.org.au" class="auth_mail" title="E-mail the corresponding author ; Simon Carsong ; Simon.Carson@cshc.co.nz" class="auth_mail" title="E-mail the corresponding author ; Ferdinandus De Loozeh ; freddelooze@austrials.com.au" class="auth_mail" title="E-mail the corresponding author ; Rod Ellis-Pegleri ; rodbep@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Leon Herone ; LeonH@chw.edu.au" class="auth_mail" title="E-mail the corresponding author ; Jeff Karraschj ; jeffkarrasch@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Helen Marshallk ; helen.marshall@adelaide.edu.au" class="auth_mail" title="E-mail the corresponding author ; Jodie Mcvernonl ; 1 ; j.mcvernon@unimelb.edu.au" class="auth_mail" title="E-mail the corresponding author ; Terry Nolanl ; t.nolan@unimelb.edu.au" class="auth_mail" title="E-mail the corresponding author ; William Rawlinsonm ; w.rawlinson@unsw.edu.au" class="auth_mail" title="E-mail the corresponding author ; Jim Reidn ; jim.reid@otago.ac.nz" class="auth_mail" title="E-mail the corresponding author ; Peter Richmondo ; Sepehr Shakibp ; ssshakib@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Russell L. Basserq ; Russell.Basser@seqirus.com" class="auth_mail" title="E-mail the corresponding author ; Gunter F. Hartelq ; 2 ; Gunter@HartelConsulting.com" class="auth_mail" title="E-mail the corresponding author ; Michael H. Laiq ; 3 ; michael_h.lai@novartis.com" class="auth_mail" title="E-mail the corresponding author ; Steven Rockmanq ; Steve.Rockman@seqirus.com" class="auth_mail" title="E-mail the corresponding author ; Michael E. Greenbergq ; 4 ; Michael.greenberg@sanofipasteur.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cross-protection ; Influenza A virus ; H1N1 subtype ; Influenza vaccine efficacy ; Seasonal influenza ; Seasonal trivalent inactivated influenza vaccine
- 刊名：Vaccine
- 出版年：2016
- 出版时间：22 September 2016
- 年：2016
- 卷：34
- 期：41
- 页码：4991-4997
- 全文大小：726 K
文摘
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Two seasonal IIV3s showed efficacy against vaccine-matched strains in adults.
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The 2009 seasonal IIV3 showed efficacy against the 2009 pandemic H1N1 strain.
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Most solicited adverse events were of mild/moderate intensity and limited duration.