Effects of 3,4-methylenedioxypyrovalerone (MDPV) pre-exposure on the aversive effects of MDPV, cocaine and lithium chloride: Implications for abuse vulnerability
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3,4-Methylenedioxypyrovalerone (MDPV), cocaine and emetic lithium chloride (LiCl) induced significant and comparable taste avoidance.

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MDPV history attenuated taste avoidance induced by MDPV and cocaine.

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MDPV history had no effect on LiCl-induced taste avoidance.

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Such attenuation may increase the abuse potential of MDPV and related drugs.

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