Encapsulation of clozapine in polymeric nanocapsules and its biological effects
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- 作者：Sylwia Łukasiewicza ; sylwia.lukasiewicz@uj.edu.pl" class="auth_mail" title="E-mail the corresponding author ; Krzysztof Szczepanowiczb ; ncszczep@cyf-kr.edu.pl" class="auth_mail" title="E-mail the corresponding author ; Karolina Podgó ; rnab ; ncpodgor@cyf-kr.edu.pl" class="auth_mail" title="E-mail the corresponding author ; Ewa Błasiaka ; ewa.blasiak@uj.edu.pl" class="auth_mail" title="E-mail the corresponding author ; Nather Majeedc ; nathermmm@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Sven Ove Ö ; gren Ogrenc ; Sven.Ove.Ogren@ki.se" class="auth_mail" title="E-mail the corresponding author ; Witold Nowakd ; witold.nowak@uj.edu.pl" class="auth_mail" title="E-mail the corresponding author ; Piotr Warszyńskib ; ncwarszy@cyf-kr.edu.pl" class="auth_mail" title="E-mail the corresponding author ; Marta Dziedzicka-Wasylewskaa ; marta.dziedzicka-wasylewska@uj.edu.pl" class="auth_mail" title="E-mail the corresponding author
- 关键词：Nanocapsule ; Clozapine ; Encapsulation ; Macrophage ; Schizophrenia
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：2016
- 出版时间：1 April 2016
- 年：2016
- 卷：140
- 期：Complete
- 页码：342-352
- 全文大小：2433 K
文摘
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Preparation of clozapine loaded nanocapsules (CLO-NCs).
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Description of the interactions of polymeric CLO-NCs with phagocytic cells.
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Description of biodistribution and the behavioral effects of CLO-NCs in vivo.
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Selection of NCs VI PGA-g(39)-PEG as promising nanocarriers for clozapine delivery.