The importance of 2D aggregates on the antimicrobial resistance of Staphylococcus aureus sessile bacteria
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- 作者：A. Miñ ; á ; naAuthor Vitae ; P.L. Schilardia ; pls@inifta.unlp.edu.ar" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae ; M. Ferná ; ndez Lorenzo de Melea ; b ; mmele@inifta.unlp.edu.ar" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae
- 关键词：Biofilm ; Antibiotic ; Persister ; Surface topography ; Staphyloccocus ; Bacterial density
- 刊名：Materials Science & Engineering C
- 出版年：2016
- 出版时间：1 April 2016
- 年：2016
- 卷：61
- 期：Complete
- 页码：199-206
- 全文大小：1330 K
文摘
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[Microstructured surfaces (MS) + antibiotic] is a good strategy for S. aureus eradication.
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Non motile bacteria remained isolated or formed small agregates on MS surfaces.
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Small agregates are more sensitive to antibiotics than dense 2D assemblages.
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Persister cells were only found on planar control surfaces after antibiotic treatment.