Gomesin acts in the immune system and promotes myeloid differentiation and monocyte/macrophage activation in mouse
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- 作者：Marcus V. Buria ; Carol C. Diasa ; Christiano M.V. Barbosaa ; Amanda Nogueira-Pedrob ; Antonio C. Ribeiro-Filhoc ; Antonio Mirandab ; amiranda@unifesp.br" class="auth_mail" title="E-mail the corresponding author ; Edgar J. Paredes-Gameroa ; c ; paredes.gamero@gmail.com" class="auth_mail" title="E-mail the corresponding author ; edgar.gamero@unifesp.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Antimicrobial peptide ; Gomesin ; Immunomodulatory activity ; Macrophage activation
- 刊名：Peptides
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：85
- 期：Complete
- 页码：41-45
- 全文大小：858 K
文摘
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Gomesin is a β-hairpin antimicrobial peptide.
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Immunesystem of mice treated with gomesin was evaluated.
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Hematopoietic progenitors and B cells increased by treatment.
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Modulation of macrophages and its function were observed.