Macromolecular iron-chelators via RAFT-polymerization for the inhibition of methicillin-resistant Staphylococcus aureus growth
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- 作者：Junpei Lia ; Eniola D. Olaleyeb ; Xiaole Kongc ; Tao Zhoud ; Yongmin Mae ; Jagoda Jurachc ; Osamah Al Rugaieb ; f ; Robert C. Hiderc ; Guoqing Zhanga ; gz6m@virginia.edu" class="auth_mail" title="E-mail the corresponding author ; Selwa Alsamb ; Vincenzo Abbatec ; vincenzo.abbate@kcl.ac.uk" class="auth_mail" title="E-mail the corresponding author
- 关键词：MRSA ; Hydroxypyridinones ; Iron-binding polymers
- 刊名：Polymer
- 出版年：2016
- 出版时间：22 March 2016
- 年：2016
- 卷：87
- 期：Complete
- 页码：64-72
- 全文大小：847 K
文摘
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HPO-functionalized iron chelating polymers were synthesized from RAFT-based PGMA.
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The synthetic method of the resulting materials is simple with high yield and low cost.
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Homopolymers were identified as new antimicrobial agents against MRSA.
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This versatile synthetic procedure can be adopted to prepare a wide range of polymeric chelators.