Spinal Schwannoma and Meningioma Mimicking a Single Mass at the Craniocervical Junction Subsequent to Remote Radiation Therapy for Acne Vulgaris

详细信息    查看全文

• 作者：Brandon D. Liebelt¹ ; ^{bdliebelt@houstonmethodist.org" class="auth_mail" title="E-mail the corresponding author} ; Ali S. Haider¹ ; William J. Steele¹ ; Chandan Krishna² ; J. Bob Blacklock¹
• 关键词：Meningioma ; Radiation-induced tumor ; Schwannoma ; Skull base tumor
• 刊名：World Neurosurgery
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：93
• 期：Complete
• 页码：484.e13-484.e16
• 全文大小：2264 K

文摘

Schwannomas and meningiomas are relatively common tumors of the nervous system. They have been reported in the literature as existing concurrently as a single mass, but very rarely have they been shown to present at the craniocervical junction.

Case Description

We present a rare and interesting case of a patient previously treated with radiation therapy for acne vulgaris and who presented to us with a concurrent schwannoma and meningioma of the craniocervical junction mimicking a single mass.

Conclusions

These tumors can be solitary or mixed masses, and are known to be associated with certain disease processes such as long-term sequelae of radiation therapy and neurofibromatosis type 2. The precise mechanism behind the formation of these tumors is unknown; however, molecular cues in the tumor microenvironment may play a role.