An HcpR paralog of Desulfovibrio gigas provides protection against nitrosative stress
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- 作者：Sofia M. da Silva ; Catarina Amaral ; Susana S. Neves ; Cá ; tia Santos ; Catarina Pimentel ; pimentel@itqb.unl.pt" class="auth_mail" title="E-mail the corresponding author ; Claudina Rodrigues-Pousada ; claudina@itqb.unl.pt" class="auth_mail" title="E-mail the corresponding author
- 关键词：BI ; Bayesian inference ; BS ; bootstrap ; CRP/FNR ; cAMP receptor protein/fumarate and nitrate reductase regulatory protein ; Frdx ; ferredoxin ; GSNO ; S-nitrosoglutathione ; Hcp ; hybrid cluster protein ; HGT ; horizontal gene transfer ; ML ; maximum likelihood ; MP ; maximum parsimony ; NO ; nitric oxide ; PP ; posterior probability ; RNS ; reactive nitrogen species ; ROO ; rubredoxin oxygen reductase ; SRB ; sulfate reducing bacteria
- 刊名：FEBS Open Bio
- 出版年：2015
- 出版时间：2015
- 年：2015
- 卷：5
- 期：Complete
- 页码：594-604
- 全文大小：3731 K
文摘
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Desulfovibrio gigas genome encodes two HcpR paralogs, HcpR1 and HcpR2.
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Cells lacking HcpR1 are less tolerant to NO.
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HcpR1 regulates the expression of several genes related to nitrogen metabolism.
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Phylogenetic analyses indicate that the presence of HcpR paralogs is a common finding among Desulfovibrio species.