Deciphering the interaction of bovine heart cystatin with ZnO nanoparticles: Spectroscopic and thermodynamic approach

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• 作者：Aamir Sohail^a ; Mohd. Faraz^b ; ^c ; Hussain Arif^a ; Sheraz Ahmad Bhat^a ; Azad Alam Siddiqui^a ; Bilqees Bano^a ; ^{basiddiqui@hotmail.com} ; ^{banob890@gmail.com}
• 关键词：ANS ; 8-Anilinonaphthalene-1-sulfonic acid ; BHC ; Buffalo heart cystatin ; CD ; Circular dichroism ; FTIR ; Fourier transform infrared ; ITC ; Isothermal titration calorimetry ; NPs ; Nanoparticles ; SDS ; Sodium dodecyl sulphate ; SEM ; Scanning electron microscopy ; TEM ; Transmission electron microscopy ; UV ; Ultraviolet ; ZnO ; Zinc oxide
• 刊名：International Journal of Biological Macromolecules
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：95
• 期：Complete
• 页码：1056-1063
• 全文大小：2229 K
• 卷排序：95

文摘

ZnO nanoparticles synthesis and characterization. Interaction of ZnO nanoparticles with BHC purified from bovine heart. Activity assessment, spectral properties and thermodynamic parameters of binding of BHC upon ZnO-NPs exposure and microscopic studies. Assessment of BHC-ZnO-NPs interaction mechanism and toxic effects of ZnO-NPs on BHC and probable implications on the biological system(s).