The difficulty in selecting patients for cytoreductive nephrectomy: An evaluation of previously described predictive models

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• 作者：Brandon J. Manley ; M.D.^a ; Daniel M. Tennenbaum ; B.S.^a ; Emily A. Vertosick ; M.P.H.^b ; James J. Hsieh ; M.D. ; PhD^c ; Daniel D. Sjoberg ; M.A.^b ; Melissa Assel ; M.A.^b ; Nicole E. Benfante ; B.S.^a ; Seth A. Strope ; M.D. ; M.P.H.^d ; Eric Kim ; M.D.^d ; Jozefina Casuscelli ; M.D.^a ; Maria F. Becerra ; M.D.^a ; Jonathan A. Coleman ; M.D.^a ; Abraham Ari Hakimi ; M.D.^a ; Paul Russo ; M.D.^a ; ^{russop@mskcc.org}
• 关键词：Renal cell carcinoma ; Neoplasm metastasis ; Nephrectomy ; Prognosis ; Mortality
• 刊名：Urologic Oncology: Seminars and Original Investigations
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：35
• 期：1
• 页码：35.e1-35.e5
• 全文大小：292 K
• 卷排序：35

文摘

A total of 5 of 7 preoperative risk factors were predictive of overall survival. The complete model had an AUC of 0.65; 95% (CI: 0.52–0.79) in our cohort. Decision curve analysis demonstrated little benefit for applicability. Differences in patient selection and pathology may explain the differentiating factors.