BAP1 is overexpressed in black compared with white patients with Mx-M1 clear cell renal cell carcinoma: A report from the cancer genome atlas
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- 作者：David J. Paulucci ; B.A. ; John P. Sfakianos ; M.D. ; Shalini Singh Yadav ; Ph.D. ; Ketan K. Badani ; M.D. ; Ketan.badani@mountsinai.org" class="auth_mail" title="E-mail the corresponding author
- 关键词：BAP1 ; Renal cell carcinoma ; The Cancer Genome Atlas ; Racial disparities
- 刊名：Urologic Oncology: Seminars and Original Investigations
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：34
- 期：6
- 页码：259.e9-259.e14
- 全文大小：376 K
文摘
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BAP1 is overexpressed in Black compared with White patients with Mx-M1 Clear Cell Renal Cell Carcinoma.
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BAP1 overexpression is associated with decreasing pathologic stage.
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This may explain why more tumors are localized in Black vs. White patients.
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BAP1 overexpression portends distinct pathologic outcomes in Black and White patients.
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Racial stratification is needed in BAP1 biomarker studies.