Antimicrobial peptides alter early immune response to influenza A virus infection in C57BL/6 mice
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- 作者：Kim S. LeMessuriera ; Yanyan Lina ; Jonathan A. McCullersa ; b ; Amali E. Samarasinghea ; b ; asamaras@uthsc.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：H1N1 influenza ; Defensins ; Macrophage ; Dendritic cell ; Inflammation
- 刊名：Antiviral Research
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：133
- 期：Complete
- 页码：208-217
- 全文大小：1121 K
文摘
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Antimicrobial peptides may modulate host defense against influenza virus infections.
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Beta-defensin pretreatment leads to a reduction in pandemic H1N1 virus burden in the lungs.
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Beta-defensin pretreatment alters the innate immune profile in response to H1N1 influenza virus.