ID 115 - Near infrared spectroscopy as a seizure detection technology for patients with epilepsy

详细信息    查看全文

• 作者：J. Jeppesen^a ; S. Beniczky^a ; ^b ; P. Johansen^c ; P. Sidenius^d ; A. Fuglsang-Frederiksen^a
• 刊名：Clinical Neurophysiology
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：127
• 期：3
• 页码：e101
• 全文大小：35 K

文摘

Near Infrared Spectroscopy (NIRS) has proved useful in measuring significant hemodynamic changes in the brain during epileptic seizures. The advance of NIRS-technology into wireless and portable devices raises the possibility of using the NIRS-technology for portable seizure detection.

Methods

This study used NIRS to measure changes in oxygenated (HbO), deoxygenated (HbR), and total hemoglobin (HbT) at left and right side of the frontal lobe in 15 epilepsy patients (34 focal seizures) undergoing long-term video-EEG monitoring. Twelve parameters consisting of maximum increase and decrease changes of HbO, HbR and HbT during seizures (1-min before- to 3-min after seizure-onset) for left and right side, were compared with the patients’ own non-seizure periods (a 2-h period and a 30-min exercise-period). In both non-seizure periods a four minutes moving windows with maximum overlapping were applied to find non-seizure maxima of the twelve parameters.

Results

When analyzing the twelve parameters separately the positive seizure detection was in range of 6–24%.

Conclusion

NIRS did not seem to be a suitable technology for generic seizure detection given the device, settings, and methods used in this study.

Key message

There are still several challenges to overcome before the NIRS-technology can be used as home-monitoring seizure detection device.