Irradiation pretreatment can disrupt the structure of lignocellulose and modify its morphology.
Inhibitors formed during irradiation pretreatment harm yeast viability and ethanol production.
Combined strategies of irradiation pretreatment with detoxification solve the toxicity dilemma.
Yeast viability, residual glucose and ethanol yield are depended on detoxification method.
Irradiated biomass can be performed in situ detoxification in solid state without extra step.