pDGO100, a type 1 IncC plasmid from 1981 carrying ARI-A and a Tn1696-like transposon in a novel integrating element
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文摘

A 217,306 bp IncC plasmid, pDGO100, was isolated from an Escherichia coli strain isolated in 1981.

The backbone of pDGO100 is closely related to another plasmid, pRMH760, recovered from the same hospital 16 years later.

A 45.5 kb ARI-A island includes six antibiotic resistance genes: aadB, sul1, dfrA10, blaTEM, catA1, and aphA1a.

A second 46 kb insertion, identified as an integrating element, includes a Tn1696-like transposon.

Related integrating elements were found in other plasmid and in the chromosomes of Enterobacteriaceae.

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