Accuracy and interobserver agreement of diffusion-weighted imaging in pediatric inflammatory bowel disease

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• 作者：Zehour AlSabban^a ; Peter Church^b ; ¹ ; Rahim Moineddin^c ; Oscar M. Navarro^a ; Mary-Louise Greer^a ; Thomas Walters^b ; Govind B. Chavhan^a ; ^{govind.chavhan@sickkids.ca}
• 关键词：MRE ; Diffusion-weighted imaging ; Inflammatory bowel disease ; Children
• 刊名：Clinical Imaging
• 出版年：2017
• 出版时间：January-February 2017
• 年：2017
• 卷：41
• 期：Complete
• 页码：14-22
• 全文大小：1071 K
• 卷排序：41

文摘

To determine interobserver agreement (IOA) and accuracy of conventional MR enterography (MRE), qualitative diffusion, and apparent diffusion coefficient (ADC) values for detecting clinically active inflammation.MethodsMREs in 57 consecutive children with suspected inflammatory bowel disease were retrospectively reviewed.ResultsSubstantial IOA for conventional MRE (kappa=0.65) and qualitative diffusion (kappa=0.64), but fair to good IOA for ADC, (intra-class coefficient=0.63) were seen. Conventional MRE detected active clinical inflammation well (area under curve [AUC] 0.725), while qualitative diffusion and ADC did not perform well (AUC=0.572 and 0.461, respectively).ConclusionDWI can be helpful in diagnosing inflammatory bowel disease but does not perform well in identifying those with active inflammation.