Higher Stem Cell Dose Infusion after Intensive Chemotherapy Does Not Improve Symptom Burden in Older Patients with Multiple Myeloma and Amyloidosis
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- 作者：Nina Shah<sup>1sup><sup> ; sup><sup>nshah@mdanderson.org" class="auth_mail" title="E-mail the corresponding authorsup> ; Qiuling Shi<sup>2sup> ; Loretta A. Williams<sup>2sup> ; Tito R. Mendoza<sup>2sup> ; Xin Shelley Wang<sup>2sup> ; James M. Reuben<sup>3sup> ; Patrick M. Dougherty<sup>4sup> ; Qaiser Bashir<sup>1sup> ; Muzaffar H. Qazilbash<sup>1sup> ; Richard E. Champlin<sup>1sup> ; Charles S. Cleeland<sup>2sup> ; Sergio A. Giralt<sup>5sup>
- 关键词：Myeloma ; Transplantation ; Symptom burden
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：22
- 期：2
- 页码：226-231
- 全文大小：816 K
文摘
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We examined the effect of stem cell dose on symptom burden during autologous transplantation.
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Severe symptoms were fatigue, lack of appetite, drowsiness, disturbed sleep, and pain.
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There were no differences in symptom burden between the 2 groups during transplantation.
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Higher stem cell dose did not yield faster hematologic recovery or lower IL-6 levels.