Imaging the human microcirculation during cardiopulmonary resuscitation in a hypothermic victim of submersion trauma

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• 作者：Paul W.G. Elbers ; Antonius J. Craenen ; Antoine Driessen ; Marco C. Stehouwer ; Luuk Munsterman ; Mir ; a Prins ; Mat van Iterson ; Peter Bruins ; Can Ince
• 关键词：Microcirculation ; Sidestream dark field imaging ; Cardiopulmonary resuscitation ; Mechanical compression/decompression ; Hypothermia ; Extracorporeal circulation ; Cardiopulmonary bypass ; Submersion ; Trauma
• 刊名：Resuscitation
• 出版年：2010
• 出版时间：January 2010
• 年：2010
• 卷：81
• 期：1
• 页码：123-125
• 全文大小：225 K

文摘

The microcirculation is essential for delivery of oxygen and nutrients to tissue. However, the human microvascular response to cardiopulmonary resuscitation (CPR) is unknown. We report on the first use of sidestream dark field imaging to assess the human microcirculation during CPR with a mechanical chest compression/decompression device (mCPR). mCPR was able to provide microvascular perfusion. Capillary flow persisted even during brief mCPR interruption. However, indices of microvascular perfusion were low and improved vastly after return of spontaneous circulation. Microvascular perfusion was relatively independent from blood pressure. The microcirculation may be a useful monitor for determining the adequacy of CPR.