The relief of dry eye signs and symptoms using a combination of lubricants, lid hygiene and ocular nutraceuticals

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• 作者：William Ngo^a ; ^{wngo@uwaterloo.ca} ; Sruthi Srinivasan^a ; Diane Houtman^b ; Lyndon Jones^a
• 关键词：TheraTears ; SteriLid ; Nutrition ; Nutraceutical ; Dry eye
• 刊名：Journal of Optometry
• 出版年：2017
• 出版时间：January-March 2017
• 年：2017
• 卷：10
• 期：1
• 页码：26-33
• 全文大小：882 K
• 卷排序：10

文摘

To determine the combined effect of TheraTears® Lubricant Eye Drops, TheraTears® SteriLid Eyelid Cleanser, and TheraTears® Nutrition on dry eye signs and symptoms.MethodsThis prospective study enrolled 28 dry eye participants. Participants were instructed to use the Lubricant Eye Drops at least 2–4× a day, SteriLid 1–2× a day, and Nutrition 3 gel caps once a day. Participants were followed up at baseline, 1 month and 3 months. Outcome variables were the Ocular Surface Disease Index (OSDI), Symptom Assessment iN Dry Eye (SANDE) questionnaire, non-invasive tear break-up time (NIBUT), osmolarity, number of meibomian glands blocked (#MG blocked), meibum quality, eyelid margin features, Schirmer's test, tear film lipid layer thickness (LLT), meniscus height, corneal and conjunctival staining.ResultsTwenty participants (mean age = 43, from 23 to 66, 17F, 3M) completed the study. Participants reported having used, on average, the Lubricant Eye Drop 2.4×/day, the SteriLid 1.1×/day, and the Nutrition 3 gel caps 1×/day. There was a significant change over time (p < 0.05) for OSDI (−21.2 points), SANDE (−32.4 points), NIBUT (+0.43 s), eyelid margin features (−1.1 grade), meibum quality (−1.0 grade), and #MG blocked (−4.0 glands).ConclusionBy using a combination of TheraTears® Lubricant Eye Drop, SteriLid, and Nutrition, patients experience significant relief in both dry eye symptoms and signs.