Symptom quality versus quantity in judging prognosis: Using NESARC predictive validators to locate uncomplicated major depression on the number-of-symptoms severity continuum

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• 作者：Jerome C. Wakefield^a ; ^{jw111@nyu.edu} ; Mark F. Schmitz^b
• 关键词：CI ; confidence interval ; CMMD ; complicated major depressive disorder ; DSM-5 ; Diagnostic and Statistical Manual of Mental Disorders ; fifth edition ; DSM-IV ; Diagnostic and Statistical Manual of Mental Disorders ; fifth edition ; GAD ; generalized anxiety disorder ; mD ; subthreshold (or &ldquo ; minor&rdquo ; ) depression ; MDD ; major depressive disorder ; MDE ; major depressive episode ; NESARC ; National Epidemiologic Survey on Alcohol and Related Conditions ; non-MDD ; no MDD history ; UMDD ; uncomplicated major
• 刊名：Journal of Affective Disorders
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：208
• 期：Complete
• 页码：325-329
• 全文大小：387 K
• 卷排序：208

文摘

Uncomplicated MDD (UMDD) by definition excludes six pathology-suggestive features. Pathology validators were 3-year follow-up rates of MDE, GAD, mania, suicidality. UMDD resembles subthreshold depression, not other MDD, in validator rates. A symptom count is inadequate for assessing MDD predictive-validator severity. Uncomplicated MDD's relatively benign prognosis should impact treatment decisions.