The role of total body irradiation (TBI) as a conditioning regime for paediatric acute lymphoblastic leukaemia: A discussion of the evidence
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文摘

TBI regimes have adverse long term effects on development, particularly on growth.

Chemotherapy only regimes have long term effects that impact on development.

TBI is a superior to chemotherapy only conditioning regimes for paediatric ALL.

Research is being undertaken to refine TBI techniques to reduce overall toxicity.

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