The Prognostic Significance of Cardiac Structure and Function in Atrial Fibrillation: The ENGAGE AF-TIMI 48 Echocardiographic Substudy
详细信息 查看全文
- 作者：Deepak K. Gupta ; MDa ; b ; d.gupta@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author ; Robert P. Giugliano ; MDc ; Christian T. Ruff ; MDc ; Brian Claggett ; PhDd ; Sabina Murphy ; PhDc ; Elliott Antman ; MDc ; Michele F. Mercuri ; MD ; PhDe ; Eugene Braunwald ; MDc ; Scott D. Solomon ; MDd ; for the Effective Anticoagulation with Factor Xa Next Generation in AF&ndash ; Thrombolysis in Myocardial Infarction 48 (ENGAGE AF&ndash ; IMI 48) Echocardiographic Study Investigators
- 关键词：Atrial fibrillation ; ENGAGE AF&ndash ; TIMI 48 ; Echocardiography ; Thromboembolism ; Stroke ; Death
- 刊名：Journal of the American Society of Echocardiography
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：29
- 期：6
- 页码：537-544
- 全文大小：747 K
文摘
- •
In 971 moderate- to high-risk subjects (CHADS2 score ≥ 2) with AF enrolled in the echocardiographic substudy of ENGAGE AF–TIMI 48, death was more frequent than thromboembolism.
- •
Larger LV size and higher filling pressures were associated with increased risks for death.
- •
Neither left atrial nor LV measures were associated with thromboembolic risk.
- •
LV size and filling pressures may help identify patients with AF at increased risk for death.