Antimicrobial effects of Lactobacillus plantarum and Lactobacillus acidophilus against multidrug-resistant enteroaggregative Escherichia coli
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- 作者：Manesh Kumara ; Pankaj Dhakaa ; Deepthi Vijaya ; Jess Vergisa ; Vysakh Mohana ; Ashok Kumara ; Nitin V. Kurkureb ; Sukhadeo B. Barbuddhec ; S.V.S. Malika ; Deepak B. Rawoola ; deepak.rawool@yahoo.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Enteroaggregative Escherichia coli ; Probiotics ; Lactobacillus plantarum ; Lactobacillus acidophilus ; Drug resistance
- 刊名：International Journal of Antimicrobial Agents
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：48
- 期：3
- 页码：265-270
- 全文大小：616 K
文摘
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First study to evaluate antibacterial effect of probiotic strains against MDR-EAEC.
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In vitro, probiotic strains in synergy were more effective against MDR-EAEC.
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Probiotic-treated mice cleared MDR-EAEC on Day 5 post-treatment.
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Histopathological changes were regenerative or normal in probiotic-treated mice.
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Probiotics can serve as alternative therapeutics to curb MDR-EAEC infections.