Claudin tight junction proteins in rainbow trout (Oncorhynchus mykiss) skin: Spatial response to elevated cortisol levels
详细信息 查看全文
- 作者：Julia Gauberg ; Dennis Kolosov ; Scott P. Kelly ; spk@yorku.ca
- 关键词：Skin ; Epidermis ; Cortisol ; Tight junction ; Claudin ; Osmoregulation
- 刊名：General and Comparative Endocrinology
- 出版年：2017
- 出版时间：1 January 2017
- 年：2017
- 卷：240
- 期：Complete
- 页码：214-226
- 全文大小：2496 K
- 卷排序：240
文摘
A first look at regional claudin (cldn) abundance in fish skin. Corticosteroid receptor (CR) abundance regionally differs in fish skin. Cortisol has region specific effects on skin cldns and CR abundance. Only ventral skin 11β-hydroxysteroid dehydrogenase responds to elevated cortisol. Endocrine-mediated regulation of fish skin barrier properties are complex & dynamic.