Exercise in pregnancy: an association with placental weight?

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• 作者：Gunvor Hilde ; PT ; PhD^a ; Anne Eskild ; MD ; PhD^a ; ^b ; Katrine Mari Owe ; PhD^c ; ^d ; Kari Bø ; PT ; PhD^e ; Elisabeth K. Bjelland ; PhD^d ; ^f ; ^{Elisabeth.Krefting.Bjelland@ahus.no}
• 关键词：birthweight ; exercise ; Norwegian Mother and Child Cohort Study ; placental weight ; pregnancy
• 刊名：American Journal of Obstetrics and Gynecology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：216
• 期：2
• 页码：168.e1-168.e9
• 全文大小：310 K
• 卷排序：216

文摘

Women with high levels of physical exercise have an increased demand for oxygen and nutrients. Thus, in pregnancies of women with high levels of exercise, it is conceivable that the supply of oxygen and nutrients to the placenta is suboptimal, and growth could be impaired.ObjectiveThe objective was to study the association of frequency of exercise during pregnancy with placental weight and placental to birthweight ratio.Study DesignThis was a prospective study of 80,515 singleton pregnancies in the Norwegian Mother and Child Cohort Study. Frequency of exercise was self-reported by a questionnaire at pregnancy weeks 17 and 30. Information on placental weight and birthweight was obtained by linkage to the Medical Birth Registry of Norway.ResultsPlacental weight decreased with increasing frequency of exercise (tests for trend, P < .001). For nonexercisers in pregnancy week 17, the crude mean placental weight was 686.1 g compared with 667.3 g in women exercising ≥6 times weekly (difference, 18.8 g; 95% confidence interval, 12.0–25.5). Likewise, in nonexercisers in pregnancy week 30, crude mean placental weight was 684.9 g compared with 661.6 g in women exercising ≥6 times weekly (difference, 23.3 g; 95% confidence interval, 14.9–31.6). The largest difference in crude mean placental weight was seen between nonexercisers at both time points and women exercising ≥6 times weekly at both time points (difference, 31.7 g; 95% confidence interval, 19.2–44.2). Frequency of exercise was not associated with placental to birthweight ratio.ConclusionWe found decreasing placental weight with increasing frequency of exercise in pregnancy. The difference in placental weight between nonexercisers and women with exercising ≥6 times weekly was small and may have no clinical implications.