Sensitive detection of estradiol based on ligand binding domain of estrogen receptor and gold nanoparticles

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• 作者：Pimchanok Busayapongchai^a ; Sineenat Siri^b ; ^{ssinee@sut.ac.th}
• 关键词：Colorimetric detection ; Co-activator ; Estradiol ; Estrogen receptor ; Gold nanoparticles
• 刊名：Analytical Biochemistry
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：518
• 期：Complete
• 页码：60-68
• 全文大小：1625 K
• 卷排序：518

文摘

Highly sensitive colorimetric assay for detecting 17β-estradiol was developed. The assay is based on LBD-ERα, RID-SRC1 and label-free AuNPs. The limit of detection of the assay is at 1.20 × 10−15 M of 17β-estradiol.