Plasma soluble neuregulin-1 as a diagnostic biomarker for Alzheimer's disease
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- 作者：Keun-A Changa ; 1 ; Ki Young Shinb ; 1 ; Eunjoo Nama ; Yeong-Bae Leec ; Cheil Moond ; Yoo-Hun Suha ; yhsuh@gachon.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Sang Hyung Leee ; nslee@snu.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Alzheimer's disease ; Beta amyloid ; Soluble NRG-1 ; Blood plasma ; Biomarker
- 刊名：Neurochemistry International
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：97
- 期：Complete
- 页码：1-7
- 全文大小：525 K
文摘
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The levels of sNRG-1 were highly increased in the plasma of the AD patients compared with the healthy control subjects.
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The sNRG-1 level of the moderate AD group was significantly higher than that of the healthy control subjects.
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There was no significant difference between the levels of sNRG-1 of the females and the males.
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The level of Aβ, S100a9 or α-Syn in the plasma of the AD patients was not higher than that of the healthy control subjects.