Phomoxins B and C: Polyketides from an endophytic fungus of the genus Eupenicillium
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- 作者：Rohan A. Davis ; Vesna Andjic ; Michael Kotiw and Roger G. Shivas
- 关键词：Endophytic fungus ; Eupenicillium sp. ; Glochidion ferdinandi ; Natural products ; Polyketides ; Phomoxin B ; Phomoxin C ; Eupenoxide ; Cyclic carbonate
- 刊名：Phytochemistry
- 出版年：2005
- 出版时间：December 2005
- 年：2005
- 卷：66
- 期：23
- 页码：2771-2775
- 全文大小：117 K
文摘
Chemical investigations of the culture broth from an endophytic fungus Eupenicillium sp. have afforded two natural products phomoxins B (1) and C (2) as well as the previously reported fungal metabolite eupenoxide (3). Compounds 1 and 2 both contain a cyclic carbonate moiety that is rare among natural products. This paper reports the full spectroscopic characterisation of phomoxins B (1) and C (2) by NMR, UV, IR and MS data. All compounds were inactive against a panel of nosocomial microbes.