Interleukin-17 acts as double-edged sword in anti-tumor immunity and tumorigenesis

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• 作者：Xin Qian^a ; ¹ ; ^{xinqiantj@163.com} ; Hankui Chen^b ; ¹ ; ^{HANKUI_CHEN@rush.edu} ; Xiaofeng Wu^a ; ^{Wu-8921324@qq.com} ; Ling Hu^c ; ^{232836909@qq.com} ; Qi Huang^d ; ^{huangqi66@126.com} ; Yang Jin^d ; ^{whuhjy@126.com}
• 关键词：Interleukin (IL)-17 ; Tumorigenesis ; Tumor immunity ; Angiogenesis ; Cytokine
• 刊名：Cytokine
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：89
• 期：Complete
• 页码：34-44
• 全文大小：948 K
• 卷排序：89

文摘

Th17 cell, γδ-T cell and non-immune cells, including tumor cell, may produce IL-17. IL-17 enhances tumor angiogenesis and promotes immune evasion. IL-17 recruits immune cell infiltration and enhances activity.