Ubiquitin Receptor Protein UBASH3B Drives Aurora B Recruitment to Mitotic Microtubules
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- 作者：Ksenia Krupina1 ; Charlotte Kleiss1 ; Thibaud Metzger1 ; Sadek Fournane1 ; Stephane Schmucker1 ; Kay Hofmann2 ; Benoit Fischer1 ; 6 ; Nicodeme Paul3 ; Iain Malcolm Porter4 ; Wolfgang Raffelsberger1 ; 5 ; Olivier Poch5 ; Jason Reese Swedlow4 ; Laurent Brino1 ; Izabela Sumara1 ; sumara@igbmc.fr" class="auth_mail" title="E-mail the corresponding author
- 关键词：mitosis ; ubiquitin ; Aurora B ; chromosome segregation ; ubiquitin receptor ; UBASH3B
- 刊名：Developmental Cell
- 出版年：2016
- 出版时间：11 January 2016
- 年：2016
- 卷：36
- 期：1
- 页码：63-78
- 全文大小：8269 K
文摘
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Ubiquitin binding domain protein UBASH3B interacts with ubiquitylated Aurora B
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Aurora B association with microtubules is determined prior to anaphase
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UBASH3B forms a complex with MKlp2 to target Aurora B to microtubules
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Chromosome segregation is controlled by the Aurora B-UBASH3B pathway