- 作者：Na Wang ; Dong Zhao ; Jing Liu ; Jun Liu ; Cheuk-Man Yu ; Wei Wang ; Jiayi Sun ; Yan Li ; Fenghe Du ; on behalf of the BRIG project
- 关键词：Heart failure ; Acute coronary syndrome ; Prognosis
- 刊名：International Journal of Cardiology
- 出版年：2012
- 出版时间：20 September, 2012
- 年：2012
- 卷：160
- 期：1
- 页码：15-19
- 全文大小：442 K
Background
Treatments of acute coronary syndrome (ACS) and heart failure (HF) have progressed greatly in the past decades. However, few data are currently available regarding the impact of HF on the in-hospital outcomes of ACS patients, under current treatment status, in China.Methods
A total of 65 hospitals from all 31 provinces of mainland China and the Hong Kong special administrative region were recruited using a multistage non-randomized sampling approach. A questionnaire was completed according to the medical records of 3168 ACS patients, of which 706 (22.3 % ) had acute HF and 262 (8.3 % ) HF patients did not have an episode of acute HF during hospitalization.
Results
The rates of in-hospital mortality and composite end-point events (death, myocardial re-/infarction, serious arrhythmia and stroke) of acute HF patients were significantly higher than those of HF patients without an acute episode and patients without HF. After adjustment for other factors (including age, ACS types and in-hospital treatments, etc.), acute HF remained to be a potent independent predictor of in-hospital mortality and composite end-point events for ACS patients (OR = 7.50, 95 % CI = 4.32-13.02 and OR = 2.74, 95 % CI = 2.15-3.48, respectively). The utilization rates of guideline recommended treatments for ACS complicating HF, such as ¦Â-blockers (67.6 % ) and PCI (17.4 % ), were low in the acute HF patients.
Conclusions
Under current treatment status, acute HF during hospitalization still rendered higher rates of in-hospital mortality and composite end-point events in the studied ACS patients in China.