Beneficial effects of fenugreek glycoside supplementation in male subjects during resistance training: A randomized controlled pilot study

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• 作者：Sachin Wankhede^a ; ^{drsachinindus@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Vishwaraman Mohan^b ; Prasad Thakurdesai^b
• 关键词：Anabolic ; Androgenic ; Fenugreek seeds ; Glycosides ; Randomized controlled study ; Resistance training
• 刊名：Journal of Sport and Health Science
• 出版年：2016
• 出版时间：June 2016
• 年：2016
• 卷：5
• 期：2
• 页码：176-182
• 全文大小：371 K

文摘

To evaluate the efficacy and safety of the glycoside fraction of fenugreek (Trigonella foenum-graecum) seeds (Fenu-FG) on physiological parameters related to muscle anabolism, androgenic hormones, and body fat in healthy male subjects during an 8-week resistance training program using a prospective, randomized, double-blind, placebo controlled design.

Methods

Sixty healthy male subjects were randomized to ingest capsules of Fenu-FG (1 capsule of 300 mg, twice per day) or the matching placebo at a 1:1 ratio. The subjects participated in a supervised 4-day per week resistance-training program for 8 weeks. The outcome measurements were recorded at recruitment (baseline) and at the end of the treatment (8 weeks). The efficacy outcome included serum testosterone (total and free) levels, muscle strength and repetitions to failure, metabolic markers for anabolic activity (serum creatinine and blood urea nitrogen), and % body fat. The standard safety measurements such as adverse events monitoring, vital signs, hematology, biochemistry, and urinalysis were performed.

Results

Fenu-FG supplementation demonstrated significant anabolic and androgenic activity as compared with the placebo. Fenu-FG treated subjects showed significant improvements in body fat without a reduction in muscle strength or repetitions to failure. The Fenu-FG supplementation was found to be safe and well-tolerated.

Conclusion

Fenu-FG supplementation showed beneficial effects in male subjects during resistance training without any clinical side effects.