• 作者：Ana Fern&#225 ; ndez-Tresguerres Centeno^a ; ^{aftresguerres@gmail.com} ; Fernando Alfageme Rold&#225 ; n^a ; Isabel Buró ; n Á ; lvarez^a ; Raquel Rodrí ; guez S&#225 ; nchez^b ; Cristina Villegas Fern&#225 ; ndez^a
• 关键词：Plasma rico en plaquetas ; Mesoterapia ; Rejuvenecimiento cutá ; neo ; Ecografí ; a cutá ; nea
• 刊名：Piel
• 出版年：2013
• 出版时间：February, 2013
• 年：2013
• 卷：28
• 期：2
• 页码：69-74
• 全文大小：669 K

Introduction

It is well known that, due to the presence of growth factors, platelet-rich plasma (PRP), is able to produce histological changes in the dermis that reproduce the process of biological tissue repair without previous damage. Biostimulation with PRP has been used clinically for skin rejuvenation of the face and neck. Skin ultrasound can be helpful to evaluate several aspects of skin aging. This study was designed to perform an objective evaluation of the beneficial effects of this treatment on skin aging.

Material and methods

Autologus PRP was injected by mesotherapy in 10 women, aged between 45 and 60 years, in the face, neck and cleavage. Three-monthly sessions were carried out and the final results were measured 1 month after the final treatment. Pictures were taken and skin ultrasound was performed of the same area of the face before and after the treatment.

Results

All patients noted an improvement in their skin quality: the skin was brighter, more hydrated, more compact and plumper. An increase of dermal thickness and a decrease in subepidermic low echogenic band (SLEB) was observed on skin ultrasound. However, this improvement was not statistically significant, probably due to the small number of patients.

Conclusions

Biotestimulation with autologous PRP improved skin quality and reversed ultrasound signs of skin aging. More studies are required to confirm these results.