LPM and LPG were prepared from alginate and studied side-by-side.
LPM and LPG derivatives containing −PO32−, −PO2H− and −SO3− were synthesized.
SO3− modification of LPM and LPG enhanced the anticoagulant and FGFs/FGFR1c signaling activation activities.
Sulfated LPG had better heparin-like activities than sulfated LPM.